KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSP90AB1
All Species:
38.48
Human Site:
T14
Identified Species:
65.13
UniProt:
P08238
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08238
NP_031381.2
724
83264
T14
H
G
E
E
E
V
E
T
F
A
F
Q
A
E
I
Chimpanzee
Pan troglodytes
A5A6K9
733
84754
T19
M
E
E
E
E
V
E
T
F
A
F
Q
A
E
I
Rhesus Macaque
Macaca mulatta
XP_001098520
724
83571
T14
H
G
E
E
E
V
E
T
F
A
F
Q
A
E
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P11499
724
83307
T14
H
G
E
E
E
V
E
T
F
A
F
Q
A
E
I
Rat
Rattus norvegicus
P34058
724
83263
T14
H
G
E
E
E
V
E
T
F
A
F
Q
A
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518700
789
90657
T14
H
G
E
E
E
V
E
T
F
A
F
Q
A
E
I
Chicken
Gallus gallus
Q04619
725
83409
T14
H
G
E
D
E
V
E
T
F
A
F
Q
A
E
I
Frog
Xenopus laevis
NP_001086624
722
82939
T14
N
G
E
E
E
V
E
T
F
A
F
Q
A
E
I
Zebra Danio
Brachydanio rerio
O57521
725
83339
T13
R
Q
E
E
E
A
E
T
F
A
F
Q
A
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02828
717
81847
F8
M
P
E
E
A
E
T
F
A
F
Q
A
E
I
A
Honey Bee
Apis mellifera
XP_395168
718
82735
T14
T
K
A
E
D
V
E
T
F
A
F
Q
A
E
I
Nematode Worm
Caenorhab. elegans
Q18688
702
80265
F8
M
S
E
N
A
E
T
F
A
F
Q
A
E
I
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P27323
700
80617
A8
M
A
D
A
E
T
F
A
F
Q
A
E
I
N
Q
Baker's Yeast
Sacchar. cerevisiae
P02829
709
81388
F8
M
A
S
E
T
F
E
F
Q
A
E
I
T
Q
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86
95.1
N.A.
N.A.
99.1
99.5
N.A.
86.8
94.7
92.4
91.4
N.A.
78.4
81.3
75.4
N.A.
Protein Similarity:
100
93.4
96.1
N.A.
N.A.
99.5
99.8
N.A.
87.5
97.7
96.6
97
N.A.
88.5
89.9
86.8
N.A.
P-Site Identity:
100
86.6
100
N.A.
N.A.
100
100
N.A.
100
93.3
93.3
80
N.A.
13.3
73.3
6.6
N.A.
P-Site Similarity:
100
86.6
100
N.A.
N.A.
100
100
N.A.
100
100
100
80
N.A.
13.3
80
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
69.6
61.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
83.8
78.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
8
15
8
0
8
15
79
8
15
72
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
79
79
72
15
79
0
0
0
8
8
15
72
0
% E
% Phe:
0
0
0
0
0
8
8
22
79
15
72
0
0
0
0
% F
% Gly:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
8
15
72
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% L
% Met:
36
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
8
8
15
72
0
8
8
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
8
8
15
72
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
65
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _